Details for gene set NCI_IL12-MEDIATED SIGNALING EVENTS[GSEA]

Table: GSEA Results Summary

Dataset	Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos
Phenotype	phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos
Upregulated in class	normalThy
GeneSet	NCI_IL12-MEDIATED SIGNALING EVENTS
Enrichment Score (ES)	-0.63346595
Normalized Enrichment Score (NES)	-1.6378298
Nominal p-value	0.0019047619
FDR q-value	0.0930643
FWER p-Value	0.536

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	STAT5A	2680458	695	2.835	-0.0153	No
2	IL12RB1	2230338 5420053	927	2.406	-0.0089	No
3	IL12RB2	6020465	1485	1.699	-0.0256	No
4	CCL3	2810092	1704	1.495	-0.0256	No
5	CD80	870112	1991	1.226	-0.0315	No
6	GADD45G	2510142	2057	1.175	-0.0257	No
7	TBX21	5270594	2132	1.114	-0.0210	No
8	CYLD	6590079	2137	1.107	-0.0125	No
9	TGFB1	1940162	2180	1.073	-0.0063	No
10	B2M	5080332 5130059	2327	1.000	-0.0064	No
11	ETV5	110017	2330	0.999	0.0014	No
12	NFKB1	5420358	2462	0.934	0.0016	No
13	CD8B	1940411 2570035	2590	0.852	0.0014	No
14	CCR5	1980072 5910722	2901	0.670	-0.0100	No
15	CREBBP	5690035 7040050	3008	0.616	-0.0109	No
16	MAPK8	2640195	3011	0.616	-0.0062	No
17	UBE2D3	3190452	3104	0.570	-0.0067	No
18	IL27RA	940093	3218	0.518	-0.0087	No
19	ARRB2	2060441	3420	0.442	-0.0161	No
20	CHUK	7050736	3694	0.353	-0.0281	No
21	IL12A	7100551	3870	0.305	-0.0351	No
22	IL1B	2640364	4058	0.263	-0.0432	No
23	IL18	6180039	4139	0.248	-0.0455	No
24	JAK2	3780528 6100692 6550577	4188	0.238	-0.0463	No
25	CD86	3390471 6200280	4631	0.174	-0.0688	No
26	TNF	6650603	4857	0.148	-0.0798	No
27	IL13	7040021	5348	0.110	-0.1054	No
28	BCL3	3990440	5360	0.110	-0.1051	No
29	IL4	6020537	6040	0.077	-0.1412	No
30	GZMA	3390315	6902	0.050	-0.1873	No
31	IL12B	460008	7246	0.043	-0.2055	No
32	PIK3R1	4730671	7432	0.039	-0.2152	No
33	XPO1	540707	7976	0.029	-0.2443	No
34	IL2	1770725	8133	0.026	-0.2525	No
35	GZMB	380066	9261	0.008	-0.3133	No
36	IL6	380133	9755	0.001	-0.3399	No
37	RAN	2260446 4590647	9782	0.000	-0.3413	No
38	IL27	1990324	9887	-0.001	-0.3469	No
39	IL1R1	3850377 6180128	10043	-0.004	-0.3553	No
40	PIAS2	1690301 5900647	10084	-0.005	-0.3574	No
41	JUN	840170	11408	-0.026	-0.4287	No
42	IFNG	5670592	11703	-0.032	-0.4443	No
43	MALT1	4670292	11838	-0.034	-0.4513	No
44	ATM	3610110 4050524	11988	-0.038	-0.4590	No
45	SRC	580132	12487	-0.050	-0.4855	No
46	IL18RAP	3850088	12491	-0.050	-0.4853	No
47	PIK3CA	6220129	12692	-0.056	-0.4957	No
48	FBXW11	6450632	12804	-0.059	-0.5012	No
49	SYK	6940133	12894	-0.062	-0.5055	No
50	STAT6	1190010 5720019	12978	-0.065	-0.5095	No
51	REL	360707	13327	-0.079	-0.5277	No
52	BIRC2	2940435 4730020	13602	-0.093	-0.5417	No
53	PRKCA	6400551	13968	-0.118	-0.5605	No
54	FOS	1850315	14050	-0.124	-0.5639	No
55	IL17A	4280369	14097	-0.128	-0.5654	No
56	STAT4	1660373 3130019	14189	-0.136	-0.5692	No
57	CCL4	50368 430047	14269	-0.144	-0.5724	No
58	FRAP1	2850037 6660010	14286	-0.146	-0.5721	No
59	ERC1	1580170 2630717 6110762 6840280	14430	-0.159	-0.5786	No
60	EBI3	5340300	14685	-0.195	-0.5908	No
61	NOD2	2510050	14972	-0.257	-0.6042	No
62	FASLG	2810044	15247	-0.339	-0.6163	No
63	RIPK2	5050072 6290632	15296	-0.354	-0.6161	No
64	GADD45B	2350408	15364	-0.376	-0.6168	No
65	IL18R1	270546	15526	-0.442	-0.6220	No
66	EOMES	2100707	15670	-0.509	-0.6258	No
67	IKBKG	3450092 3840377 6590592	15750	-0.544	-0.6257	No
68	RAB7A	450433 4070112 4480324	15785	-0.560	-0.6232	No
69	PRF1	6660309	15945	-0.637	-0.6268	Yes
70	ATF2	2260348 2480441	15990	-0.670	-0.6239	Yes
71	JAK1	5910746	15995	-0.673	-0.6188	Yes
72	MAP2K3	5570193	16214	-0.811	-0.6242	Yes
73	TRAF6	4810292 6200132	16386	-0.933	-0.6261	Yes
74	IKBKB	6840072	16418	-0.950	-0.6204	Yes
75	SPHK2	2030487 4120670 4850114	16453	-0.979	-0.6145	Yes
76	MAPK9	2060273 3780209 4070397	16489	-0.997	-0.6086	Yes
77	MAPK14	5290731	16662	-1.120	-0.6091	Yes
78	TYK2	1660465 1740736	16700	-1.152	-0.6020	Yes
79	GATA3	6130068	16926	-1.380	-0.6033	Yes
80	IL2RB	4730072	17155	-1.650	-0.6027	Yes
81	IRF1	2340152 3450592 6290121 6980577	17156	-1.653	-0.5897	Yes
82	IL6ST	5890047	17300	-1.822	-0.5831	Yes
83	NFKBIA	1570152	17332	-1.860	-0.5702	Yes
84	MAP3K14	5890435	17399	-1.981	-0.5582	Yes
85	RELB	1400048	17503	-2.129	-0.5470	Yes
86	MAP2K6	1230056 2940204	17557	-2.234	-0.5324	Yes
87	NFKB2	2320670	17622	-2.349	-0.5174	Yes
88	RELA	3830075	17641	-2.379	-0.4997	Yes
89	CD28	1400739 4210093	17736	-2.566	-0.4846	Yes
90	LCK	3360142	17786	-2.667	-0.4663	Yes
91	STAT2	3780519	18002	-3.197	-0.4528	Yes
92	BCL10	2360397	18080	-3.458	-0.4298	Yes
93	IL2RA	6620450	18109	-3.560	-0.4034	Yes
94	STAT1	6510204 6590553	18110	-3.562	-0.3754	Yes
95	IL2RG	4120273	18179	-3.829	-0.3490	Yes
96	SOCS1	730139	18254	-4.161	-0.3203	Yes
97	STAT3	460040 3710341	18266	-4.219	-0.2878	Yes
98	CD4	1090010	18290	-4.362	-0.2548	Yes
99	CD3D	2810739	18306	-4.485	-0.2204	Yes
100	CD3E	3800056	18448	-5.536	-0.1845	Yes
101	TNFRSF1A	1090390 6520735	18474	-5.755	-0.1407	Yes
102	CD247	3800725 5720136	18488	-5.985	-0.0944	Yes
103	TNFAIP3	2900142	18498	-6.065	-0.0472	Yes
104	CD3G	2680288	18554	-6.817	0.0033	Yes